Phenotypes associated with this allele

• Allele Symbol: Npr3^stri
• Allele Name: strigosus
• Allele ID: MGI:1857836
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npr3^stri/Npr3^stri	involves: 129/Sv * FVB/N	MGI:3712888

Genotype
MGI:3712888

hm1

• Allelic Composition: Npr3^stri/Npr3^stri
• Genetic Background: involves: 129/Sv * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal limb bone morphology ( J:57460 )

abnormal carpal bone morphology ( J:57460 )

abnormal phalanx morphology ( J:57460 )

• delayed ossification is most noticeable at the extremities of phalanges

abnormal metacarpal bone morphology ( J:57460 )

• ossification centers not found in all metacarpals

• delayed ossification most noticeable at metacarpal extremities

abnormal axial skeleton morphology ( J:57460 )

• easily distinguished from wild-type sibs as early as 6 days of age

abnormal nucleus pulposus morphology ( J:57460 )

absent nucleus pulposus ( J:57460 )

calcified intervertebral disk ( J:57460 )

kyphosis ( J:57460 )

abnormal vertebrae morphology ( J:57460 )

• truncal vertebrae are enlarged

abnormal caudal vertebrae morphology ( J:57460 )

increased thoracic vertebrae number ( J:57460 )

• partial thoracic supernumerary vertebrae with a small rib may occur

abnormal sacral vertebrae morphology ( J:57460 )

• transverse processes are sharper and more rostrally orientated than normal

abnormal vertebrae development ( J:57460 )

abnormal intervertebral disk development ( J:57460 )

• discs are very thin

abnormal vertebral epiphyseal plate morphology ( J:57460 )

• abnormal proliferation at ventral and dorsal extremities, invading the vetebral bodies

abnormal skeleton development ( J:57460 )

delayed endochondral bone ossification ( J:57460 )

• observed in newborn mice

• evident in entire skeleton but most noticeable in fore- and hindpaws

limbs/digits/tail

abnormal limb bone morphology ( J:57460 )

abnormal carpal bone morphology ( J:57460 )

abnormal phalanx morphology ( J:57460 )

• delayed ossification is most noticeable at the extremities of phalanges

abnormal metacarpal bone morphology ( J:57460 )

• ossification centers not found in all metacarpals

• delayed ossification most noticeable at metacarpal extremities

abnormal caudal vertebrae morphology ( J:57460 )

adipose tissue

abnormal adipose tissue distribution ( J:57460 )

abnormal abdominal fat pad morphology ( J:57460 )