growth/size/body
• compared to same sex littermates
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behavior/neurological
• subtle tremors are noticeable by 2.5-3 weeks of age
• tremors do not intensify with age
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endocrine/exocrine glands
• in a small number of ovaries examined,fewer and smaller corpora lutea were observed than expected for the strain background
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reproductive system
• sperm abnormalities are similar to those seen in mice homozygous for the pink-eyed dilution deletion alleles, pbs, p6H, or p25H .
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• males have a reduced sperm number
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• in a small number of ovaries examined,fewer and smaller corpora lutea were observed than expected for the strain background
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• ovaries are fully functional when transplanted into histocompatible hosts
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cellular
• sperm abnormalities are similar to those seen in mice homozygous for the pink-eyed dilution deletion alleles, pbs, p6H, or p25H .
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• males have a reduced sperm number
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