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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		CrygdLop12
lens opacity 12
MGI:1858026
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		CrygdLop12/CrygdLop12 involves: BALB/cJ * SJL/J MGI:3796549
ht2
 		CrygdLop12/Crygd+ involves: BALB/cJ * SJL/J MGI:2175808


Genotype
MGI:3796549
hm1
Allelic
Composition		 CrygdLop12/CrygdLop12
Genetic
Background		 involves: BALB/cJ * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygdLop12 mutation (1 available); any Crygd mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
cataract ( J:60856 )
• characterized by irregular nuclear opacity that develops by one month of age
• develops mild cortical opacification with age
• early in life, the lens cortex and nuclear material extrude into the vitreous and posterior chambers




Genotype
MGI:2175808
ht2
Allelic
Composition		 CrygdLop12/Crygd+
Genetic
Background		 involves: BALB/cJ * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygdLop12 mutation (1 available); any Crygd mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
cataract ( J:60856 )
• first detectable by 1 month of age; progressive opacity with age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
cataract 2 multiple types DOID:0110235 OMIM:604307
 J:60856




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory