Phenotypes associated with this allele

• Allele Symbol: Hmga2^pg-Tg40ACha
• Allele Name: isoform C transgenic, nonhomologous insert 40A, Kiran Chada
• Allele ID: MGI:1858044
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40ACha	involves: C57BL/6J * CBA/J	MGI:3834940
ht2	Hmga2^pg-Tg40ACha/Hmga2^+	involves: C57BL/6J * CBA/J	MGI:3834943
ht3	Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40BCha	involves: C57BL/6J * CBA/J	MGI:3834941

Genotype
MGI:3834940

hm1

• Allelic Composition: Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40ACha
• Genetic Background: involves: C57BL/6J * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small adrenal glands ( J:21153 )

• 12% to 16% of wild-type

small testis ( J:21153 )

♂ • 17% smaller than expected

growth/size/body

decreased body size ( J:10325 )

decreased body weight ( J:21153 )

• 40% of wild-type at 10 weeks

proportional dwarf ( J:21153 )

• at 2 weeks of age

nervous system

abnormal brain size ( J:21153 )

• despite a 40% reduction in body weight, brain weight is 90% of wild-type

reproductive system

small testis ( J:21153 )

♂ • 17% smaller than expected

Genotype
MGI:3834943

ht2

• Allelic Composition: Hmga2^pg-Tg40ACha/Hmga2⁺
• Genetic Background: involves: C57BL/6J * CBA/J

endocrine/exocrine glands

small adrenal glands ( J:21153 )

• 58% to 67% of wild-type

small testis ( J:21153 )

♂ • 67% of wild-type

growth/size/body

decreased body weight ( J:21153 )

• 80% of wild-type at 10 weeks

nervous system

abnormal brain size ( J:21153 )

• despite an 80% reduction in body weight, brain weight is 97% of wild-type

reproductive system

small testis ( J:21153 )

♂ • 67% of wild-type

Genotype
MGI:3834941

ht3

• Allelic Composition: Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40BCha
• Genetic Background: involves: C57BL/6J * CBA/J

growth/size/body

decreased body size ( J:10325 )

decreased body weight ( J:21153 )

• at 10 weeks

proportional dwarf ( J:21153 )