Analysis Tools
mortality/aging
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• less than 40% survive to weaning
|
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• 60% of presumptive homozygotes die by weaning
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limbs/digits/tail
long toenails
(
J:14112
)
|
• seen at birth
|
|
• digits of hindlimbs twist laterally with pads facing inward
• severe on hind feet; less obvious on front feet
|
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• shortening of phalanges is so extreme only the nails define position of the toes
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syndactyly
(
J:14112
)
|
• soft tissue fusions involve digits 2 and 3, sometimes 4
|
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• metatarsals of hindlimbs twist outward more severely than in the heterozygote
|
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• on hindlimbs
• function of proximal joints is lost resulting in little or no flexing ability
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• in regions where the tail kinks
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kinked tail
(
J:14112
)
|
• seen at birth
• dorsal and upward kinking and a hook forms near the tail tip
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skeleton
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• shortening of phalanges is so extreme only the nails define position of the toes
|
|
• metatarsals of hindlimbs twist outward more severely than in the heterozygote
|
|
• on hindlimbs
• function of proximal joints is lost resulting in little or no flexing ability
|
|
• function of proximal joints of metatarsals of hindlimbs is lost resulting in little or no flexing ability
|
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• in regions where the tail kinks
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reproductive system
integument
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• severe on hind feet; less obvious on front feet
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• nails overgrow and twist, more obviosu than in the heterozygote
|
long toenails
(
J:14112
)
