Phenotypes associated with this allele

• Allele Symbol: Mv
• Allele Name: malformed vertebrae
• Allele ID: MGI:1861226
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mv/Mv	either: (involves: AKR/J * 129S1/Sv) or (involves: AKR/J * C57BL/6J) or (involves: AKR/J * C3H/HeJ)	MGI:3784527
ht2	Mv/Mv^+	either: (involves: AKR/J * 129S1/Sv) or (involves: AKR/J * C57BL/6J) or (involves: AKR/J * C3H/HeJ)	MGI:3784524

Genotype
MGI:3784527

hm1

• Allelic Composition: Mv/Mv
• Genetic Background: either: (involves: AKR/J * 129S1/Sv) or (involves: AKR/J * C57BL/6J) or (involves: AKR/J * C3H/HeJ)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality ( J:5570 )

growth/size/body

decreased fetal size ( J:5570 )

• reduced body length is noticeable by E12

skeleton

abnormal axial skeleton morphology ( J:5570 )

abnormal thoracic cage morphology ( J:5570 )

abnormal vertebral column morphology ( J:5570 )

embryo

abnormal somite development ( J:5570 )

abnormal somite shape ( J:5570 )

• abnormal somite shape due to asymmetric fusions is noticeable at E16

limbs/digits/tail

abnormal tail morphology ( J:5570 )

short tail ( J:5570 )

• tail does not extend much beyond pelvic girdle

Genotype
MGI:3784524

ht2

• Allelic Composition: Mv/Mv⁺
• Genetic Background: either: (involves: AKR/J * 129S1/Sv) or (involves: AKR/J * C57BL/6J) or (involves: AKR/J * C3H/HeJ)

limbs/digits/tail

abnormal tail morphology ( J:5570 )

kinked tail ( J:5570 )

• kink at tail tip

• noticeable a few days after birth

skeleton

abnormal axial skeleton morphology ( J:5570 )

abnormal rib morphology ( J:5570 )

rib fusion ( J:5570 )

• identified at E13 in some mice