Phenotypes associated with this allele

• Allele Symbol: Scr
• Allele Name: scruffy
• Allele ID: MGI:1861470
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scr/Scr	involves: 101/H * C3H/HeH	MGI:5632503
ht2	Scr/Scr^+	involves: 101/H * C3H/HeH	MGI:5632491

Genotype
MGI:5632503

hm1

• Allelic Composition: Scr/Scr
• Genetic Background: involves: 101/H * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:3458 )

integument

abnormal coat appearance ( J:3458 )

• discernable in mutant mice around 12 days of age

disheveled coat ( J:3458 )

shiny fur ( J:3458 )

waved hair ( J:3458 )

• the coat is wavier than seen for heterozygotes

wavy vibrissae ( J:3458 )

endocrine/exocrine glands

small thymus ( J:3458 )

hematopoietic system

small thymus ( J:3458 )

immune system

small thymus ( J:3458 )

Genotype
MGI:5632491

ht2

• Allelic Composition: Scr/Scr⁺
• Genetic Background: involves: 101/H * C3H/HeH

integument

abnormal coat appearance ( J:3458 )

• discernable in mutant mice around 12 days of age

disheveled coat ( J:3458 )

shiny fur ( J:3458 )

waved hair ( J:3458 )

• vibrissae are unaffected

growth/size/body

decreased body weight ( J:3458 )

• mutant mice weigh 25% less by weaning compared with normal siblings, although weights at birth are similar