Phenotypes associated with this allele

• Allele Symbol: Ve
• Allele Name: velvet coat
• Allele ID: MGI:1861629
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ve/Ve	Not Specified	MGI:3580303
ht2	Ve/Ve^+	Not Specified	MGI:3586528

Genotype
MGI:3580303

hm1

• Allelic Composition: Ve/Ve
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality ( J:6742 , J:13665 )

• at E6.5 the ectodermal portions of the egg cylinder are reduced and endoderm is loose and columnar (J:6742)

• E7 embryos showed varying ectoderm deficiencies (J:13665)

• E9 embryos formed gut, heart, and yolk sac, but had a small neural plate instead of a neural tube (J:13665)

Genotype
MGI:3586528

ht2

• Allelic Composition: Ve/Ve⁺
• Genetic Background: Not Specified

integument

abnormal coat appearance ( J:15247 )

• before weaning coat appears clumped and very silky; after weaning disheveled

disheveled coat ( J:15247 )

• weanling mice are ruffled, untidy and appear greasy

abnormal hair shaft morphology ( J:15247 )

• arrangment of medullary cells within the shaft is less uniform than in normal hair

• medullary air spaces contain extensive areas of fluid

• pigmentation in proximal part of all hair types is occasionally reduced

• there are variations in calibre and hairs bend and break easily, sometimes low in the follicle

abnormal hair follicle morphology ( J:15247 )

• epidermis fails to thin and sebaceous glands do not regress

abnormal vibrissa morphology ( J:15247 )

• between birth and two days vibrissae are close to the head and point backward

curly vibrissae ( J:15247 )

• by two weeks of age, whiskers are sligthly waved and nolonger situated backwards

abnormal epidermal layer morphology ( J:15247 )

• epidermis is irregular and less compact