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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
sgl
scraggly
MGI:1861633
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
sgl/sgl involves: C3H * C57BL/6J MGI:3512134


Genotype
MGI:3512134
hm1
Allelic
Composition
sgl/sgl
Genetic
Background
involves: C3H * C57BL/6J
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phenotype observed in females
phenotype observed in males
N normal phenotype

Phenotype of sgl/sgl mice

pigmentation
• a brownish tint throughout each hair was determined to be a consequence of an increase in the sterol ester component of the hair

immune system
• clear fluid-filled cysts are found in the intra-salivary and adjacent lymph nodes with large numbers of mast cells and plasmacytoid monocytes found at the margins of the cysts
• eyes often encrusted with discharge

vision/eye
• eyes often encrusted with discharge

integument
• a brownish tint throughout each hair was determined to be a consequence of an increase in the sterol ester component of the hair
• signs of abnormal hair growth and loss showed with the first wave of hair growth
• older mice maintain hair on the ventrum; hair on dorsum is patchy
• hair texture is coarse, hair shafts are twisted and coiled
• signs of abnormal hair growth and loss showed with the first wave of hair growth
• moderate hyperkeratosis and cyst-like inclusions
• the skin is mosaic for numbers of hair follicles and arrangement





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory