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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pmp22Tr-1H
trembler 1 Harwell
MGI:1862010
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Pmp22Tr-1H/Pmp22+ involves: BALB/cAnNCrl * C3H/HeN MGI:3794521


Genotype
MGI:3794521
ht1
Allelic
Composition
Pmp22Tr-1H/Pmp22+
Genetic
Background
involves: BALB/cAnNCrl * C3H/HeN
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pmp22Tr-1H mutation (2 available); any Pmp22 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in some mice
• impaired motor function is more severe than in Pmp22Tr-3H or Pmp22Tr-2H heterozygotes

nervous system
• Schwann cell numbers are increased compared to in wild-type mice and Pmp22Tr-3H heterozygotes
• mice exhibit axonal atrophy





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory