Phenotypes associated with this allele

• Allele Symbol: Lim2^To3
• Allele Name: total opacity 3
• Allele ID: MGI:1862040
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lim2^To3/Lim2^To3	involves: 102 * C3H/He * T STOCK	MGI:2175102
ht2	Lim2^To3/Lim2^+	involves: 102 * C3H/He * T STOCK	MGI:2175103

Genotype
MGI:2175102

hm1

• Allelic Composition: Lim2^To3/Lim2^To3
• Genetic Background: involves: 102 * C3H/He * T STOCK

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

ruptured lens capsule ( J:46338 )

• lens capsule ruptures at the posterior, and leaks lens material into the vitreous chamber

lens vacuoles ( J:46338 )

abnormal lens fiber morphology ( J:46338 )

• fibers are grossly disorganized; fibers in the central region lose their nuclei, but do not undergo orderly arrangement

disorganized secondary lens fibers ( J:46338 )

• disorganized secondary fibers are also present

cataract ( J:46338 )

total cataract ( J:34877 )

• total opacity

microphthalmia ( J:34877 , J:46338 )

abnormal vitreous body morphology ( J:46338 )

• small vitreous chamber resulting in a shrunken eye appearance

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 19 multiple types		DOID:0110263	OMIM:615277	J:46338

Genotype
MGI:2175103

ht2

• Allelic Composition: Lim2^To3/Lim2⁺
• Genetic Background: involves: 102 * C3H/He * T STOCK

vision/eye

total cataract ( J:34877 )

• total opacity

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 19 multiple types		DOID:0110263	OMIM:615277	J:46338