endocrine/exocrine glands
absent ovary
(
J:60621
)
|
|
absent testes
(
J:60621
)
|
|
homeostasis/metabolism
|
• undetectable levels of testosterone
|
|
• undetectable levels of estradiol
|
|
• elevated levels of FSH
|
reproductive system
• primordial germ cells migrate to the gonadal region at E12.0, but the proliferation of gonadal cells at E11.5 was not apparent
|
|
• atrophic
|
|
• no male accessory sex organs found in genetically identified males
|
• all mice phenotypically female, although half were genetically male
|
absent ovary
(
J:60621
)
|
|
absent testes
(
J:60621
)
|
|
• all mice phenotypically female, although half were genetically male
• no male accessory sex organs found in genetically identified males
|
|
• females did not undergo an oestrus cycle
|
infertility
(
J:60621
)
• mice were infertile
|
cellular
• primordial germ cells migrate to the gonadal region at E12.0, but the proliferation of gonadal cells at E11.5 was not apparent
|