Phenotypes associated with this allele

• Allele Symbol: awg^{Tg(GBts1env)832Pkw}
• Allele Name: transgene insertion 832, Paul Wong
• Allele ID: MGI:1889309
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	awg^Tg(GBts1env)832Pkw/awg^Tg(GBts1env)832Pkw	involves: C57BL/6J * SJL	MGI:2655678

Genotype
MGI:2655678

hm1

• Allelic Composition: awg^{Tg(GBts1env)832Pkw}/awg^{Tg(GBts1env)832Pkw}
• Genetic Background: involves: C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:43273 )

• animals die between 24-30 days of age

behavior/neurological

limb grasping ( J:43273 )

• grasping of hindlimbs when lifted by tail

tremors ( J:43273 )

• animals shake when walking

ataxia ( J:43273 )

• animals are described as having a wobbly gait and tremors when walking

abnormal gait ( J:43273 )

• wobbly gait

growth/size/body

decreased body size ( J:43273 )

• animals are described as smaller than controls

immune system

thymus atrophy ( J:43273 )

• thymic atrophy

nervous system

motor neuron degeneration ( J:43273 )

• degeneration of motor neurons was observed

hematopoietic system

thymus atrophy ( J:43273 )

• thymic atrophy

endocrine/exocrine glands

thymus atrophy ( J:43273 )

• thymic atrophy