mortality/aging
• 44% of heterozygous mutant females die in utero
|
growth/size/body
• at birth, heterozygous mutant females weigh ~83.6 +/- 4.1% of wild-type controls
|
• at weaning, heterozygous mutant females weigh ~89.5 +/- 3.7% of wild-type controls
|
integument
striated fur
(
J:46359
)
• heterozygous mutant females are first recognized at 8-10 days postnatally by the presence of dark stripes on the dorsal coat
• these stripes are more prominent than those observed in females heterozygous for the Li allele
• however, no gross abnormalities are observed in dorsal skin or hair of whole body sections and other tissues appear histologicallly normal
|