Phenotypes associated with this allele

• Allele Symbol: Tg(Bdnf)1Paus
• Allele Name: transgene insertion 1, Ralf Paus
• Allele ID: MGI:1891518
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Bdnf)1Paus/0	involves: FVB	MGI:2174825

Genotype
MGI:2174825

tg1

• Allelic Composition: Tg(Bdnf)1Paus/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal sympathetic system morphology ( J:56217 )

• abnormal sympathetic innervation: adrenergic hyperinnervation in the dorsal skin

abnormal innervation ( J:56217 )

• adrenergic hyperinnervation in the dorsal skin, most pronounced in the arrector pili muscle of hair follicles and its surrounding dermis

abnormal sensory neuron innervation pattern ( J:110609 )

• enhanced sensory innervation of the lung

abnormal adrenergic neuron morphology ( J:56217 )

• increase in the number of dermal adrenergic fibers

increased Merkel's receptor number ( J:110609 )

• increased numbers of Merkel's cells in foot pad skin

integument

short hair ( J:53271 )

• hair shorter than in controls

abnormal hair cycle ( J:53271 )

• hair follicle in advanced stages of catagen by day 16

abnormal keratinocyte morphology ( J:54992 )

• enhanced numbers of proliferating epidermal keratinocytes

thick epidermis ( J:54992 )

thin skin ( J:53271 )

• skin substantially thinner than in control