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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(BCL2L1)1Cbt
transgene insertion 1, Craig B Thompson
MGI:1926365
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(BCL2L1)1Cbt/0 Not Specified MGI:2174822


Genotype
MGI:2174822
tg1
Allelic
Composition		 Tg(BCL2L1)1Cbt/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
decreased sensitivity to skin irradiation ( J:65162 )
• greater than 5-fold reduction in the number of apoptotic cells in skin 24 hours after UV irradiation, however epidermal terminal differentiation and development are normal
abnormal keratinocyte physiology ( J:65162 )
• enhanced cell survival of keratinocytes treated with a chemotherapy-induced apoptotic stimulus, however rate of wound repair and keratinocyte proliferation are normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory