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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(ITGB1)0870Fmw
transgene insertion 0870, Fiona M Watt
MGI:1926493
Summary 7 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583543
cx2
 		Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583546
cx3
 		Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583540
cx4
 		Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583556
cx5
 		Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583559
cx6
 		Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0 		involves: C57BL/10 * CBA MGI:3583552
tg7
 		Tg(ITGB1)0870Fmw/0 involves: C57BL/10 * CBA MGI:3583562


Genotype
MGI:3583543
cx1
Allelic
Composition		 Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583546
cx2
Allelic
Composition		 Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583540
cx3
Allelic
Composition		 Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583556
cx4
Allelic
Composition		 Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583559
cx5
Allelic
Composition		 Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583552
cx6
Allelic
Composition		 Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Genotype
MGI:3583562
tg7
Allelic
Composition		 Tg(ITGB1)0870Fmw/0
Genetic
Background		 involves: C57BL/10 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
cornea scarring ( J:30249 )
• adult

immune system
eye inflammation ( J:30249 )
• exudate in cornea and eyelid, neonate
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic

endocrine/exocrine glands

integument
dermatitis ( J:30249 )
• age of onset 6 weeks, episodic
flaky skin ( J:30249 )
• age of onset 6 weeks, episodic

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
 J:30249




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory