All Phenotypes Tg(ITGA5)0844Fmw MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(ITGA5)0844Fmw
transgene insertion 0844, Fiona M Watt
MGI:1926495

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0840Fmw/0	involves: C57BL/10 * CBA	MGI:3583554
cx2	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0869Fmw/0	involves: C57BL/10 * CBA	MGI:3583555
cx3	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583556
tg4	Tg(ITGA5)0844Fmw/0	involves: C57BL/10 * CBA	MGI:3583549

Allelic Composition	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0840Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0869Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0844Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eyelids open at birth ( J:30249 )

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24