All Phenotypes Tg(ITGA5)0858Fmw MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(ITGA5)0858Fmw
transgene insertion 0858, Fiona M Watt
MGI:1926497

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0840Fmw/0	involves: C57BL/10 * CBA	MGI:3583557
cx2	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0869Fmw/0	involves: C57BL/10 * CBA	MGI:3583558
cx3	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583559
tg4	Tg(ITGA5)0858Fmw/0	involves: C57BL/10 * CBA	MGI:3583550

Allelic Composition	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0840Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0869Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

cornea scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0858Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eyelids open at birth ( J:30249 )

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

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