cellular
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• severe defects in adhesion are seen in the mammary gland ducts
• in culture myoepithelial cells are impaired in their ability to adhere to luminal epithelial cells
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endocrine/exocrine glands
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• between the luminal epithelial cells and the myoepithelial cells
• end buds formed by transplanted mammary analage display subcapsular space, dissociated cap cells, cap cell layers devoid of underlying luminal epithelial cells, regions of disrupted cap cells, and regions of invaginated cap cell layers
• breaks in the basal lamina are seen and severe adhesion defects are detected
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integument
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• end buds formed by transplanted mammary analage display subcapsular space, dissociated cap cells, cap cell layers devoid of underlying luminal epithelial cells, regions of disrupted cap cells, and regions of invaginated cap cell layers
• breaks in the basal lamina are seen and severe adhesion defects are detected
• between the luminal epithelial cells and the myoepithelial cells
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