mortality/aging
• die within a few minutes after birth
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embryo
• embryos show a lack of primary myocytes in somites between E9.5 and E10.5
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skeleton
• lack the distal parts of the ribs and thus no contacts with the sternum are made
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• lack the distal parts of the ribs
(J:24360)
• ribs are shorter than in wild-type but are somewhat longer than in Myf5tm1Jae mice
(J:31636)
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• sternum is completely ossified
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muscle
• significant decrease in muscle fibers of the deep axial muscles at several locations along the rostro-caudal axis (the deep back muscles)
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