Phenotypes associated with this allele

• Allele Symbol: Tg(Cat)370Rpw
• Allele Name: transgene insertion 370, Richard P Woychik
• Allele ID: MGI:1927810
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Cat)370Rpw/Tg(Cat)370Rpw Tht/Tht^+	involves: FVB/N	MGI:3811308
tg2	Tg(Cat)370Rpw/Tg(Cat)370Rpw	involves: FVB/N	MGI:2174827

Genotype
MGI:3811308

cx1

• Allelic Composition: Tg(Cat)370Rpw/Tg(Cat)370Rpw; Tht/Tht⁺
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

small caudal vertebrae ( J:26246 )

• bone fragments, rather than distinct vertebrae, form in the most distal part of the tail

short tail ( J:26246 )

• mice have short, thickened tails that are one-half the length of normal tails

kinked tail ( J:26246 )

• a kink is found at the end of the mouse's tail

skeleton

small caudal vertebrae ( J:26246 )

• bone fragments, rather than distinct vertebrae, form in the most distal part of the tail

Genotype
MGI:2174827

tg2

• Allelic Composition: Tg(Cat)370Rpw/Tg(Cat)370Rpw
• Genetic Background: involves: FVB/N

limbs/digits/tail

abnormal caudal vertebrae morphology ( J:26246 )

• tails have a disruption in the alignment of the last seven caudal vertebrae

• misshapen development of the posterior portion of individual vertebrae causes this misalignment

kinked tail ( J:26246 )

• first apparent ~9 days after birth

skeleton

abnormal caudal vertebrae morphology ( J:26246 )

• tails have a disruption in the alignment of the last seven caudal vertebrae

• misshapen development of the posterior portion of individual vertebrae causes this misalignment

abnormal spine curvature ( J:26246 )

• described as undulated