Phenotypes associated with this allele

• Allele Symbol: Tgm3^we-Bkr
• Allele Name: wellhaarig Bunker
• Allele ID: MGI:1929708
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tgm3^we/Tgm3^we-Bkr	involves: 129 * C57BL/10 * UW	MGI:5311631
cx2	Bloc1s6^pa/Bloc1s6^pa Tgm3^we/Tgm3^we-Bkr	involves: 129 * C57BL/10 * UW	MGI:5311432

Genotype
MGI:5311631

ht1

• Allelic Composition: Tgm3^we/Tgm3^we-Bkr
• Genetic Background: involves: 129 * C57BL/10 * UW

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

waved hair ( J:8296 )

Genotype
MGI:5311432

cx2

• Allelic Composition: Bloc1s6^pa/Bloc1s6^pa; Tgm3^we/Tgm3^we-Bkr
• Genetic Background: involves: 129 * C57BL/10 * UW

integument

abnormal coat appearance ( J:8296 )

• thoracic cavity is unusually small

waved hair ( J:8296 )

skeleton

short femur ( J:8296 )

abnormal thoracic cage shape ( J:8296 )

abnormal vertebral column morphology ( J:8296 )

lordosis ( J:8296 )

• severe curvature abnormality of the cervical and upper thoracic spine

abnormal skeleton development ( J:8296 )

• there is abnormal growth of the linear, endochondral, and radial bones

abnormal skeleton physiology ( J:8296 )

• skeletons are incompletely ossified

behavior/neurological

abnormal gait ( J:8296 )

• mice move with a waddling gait, unable to lift the quarters off the ground

limbs/digits/tail

short femur ( J:8296 )

respiratory system

small lung ( J:8296 )

atelectasis ( J:8296 )

• small lung size is a contributing factor

mortality/aging

lethality, complete penetrance ( J:8296 )

• this genotype dies between 2 and 4 weeks of age