Phenotypes associated with this allele

• Allele Symbol: Csk^tm2Sia
• Allele Name: targeted mutation 2, Shinichi Aizawa
• Allele ID: MGI:1930554
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csk^tm2Sia/Csk^tm2Sia	involves: BALB/c * C57BL/6 * CBA	MGI:2175820

Genotype
MGI:2175820

hm1

• Allelic Composition: Csk^tm2Sia/Csk^tm2Sia
• Genetic Background: involves: BALB/c * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:12623 )

• phenotype is stated to be identical to that of Csk^tm1Sia homozygotes; however, no data are presented in J:12623

embryo

absent vitelline blood vessels ( J:12623 )

incomplete embryo turning ( J:12623 )

embryonic growth arrest ( J:12623 )

embryonic growth retardation ( J:12623 )

decreased embryo size ( J:12623 )

abnormal neural tube morphology ( J:12623 )

incomplete rostral neuropore closure ( J:12623 )

open neural tube ( J:12623 )

embryo tissue necrosis ( J:12623 )

absent visceral yolk sac blood islands ( J:12623 )

growth/size/body

embryonic growth retardation ( J:12623 )

decreased embryo size ( J:12623 )

nervous system

abnormal neural tube morphology ( J:12623 )

incomplete rostral neuropore closure ( J:12623 )

open neural tube ( J:12623 )

absent olfactory bulb ( J:12623 )

abnormal cranial ganglia morphology ( J:12623 )

cellular

cellular phenotype ( J:12623 )

N

cellular necrosis ( J:12623 )

vision/eye

abnormal lens induction ( J:12623 )

hearing/vestibular/ear

abnormal otic vesicle development ( J:12623 )

cardiovascular system

absent vitelline blood vessels ( J:12623 )