Analysis Tools
mortality/aging
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• embryos die between E9.5 and E10.5
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embryo
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• 40% showed placental hemorrhaging at E9.5
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• 20% showed delayed rotation at E9.5
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• growth retardation: decreased crown rump and head length by E9.5, decreased somite number by E10.5
• 20% showed delayed rotation at E9.5
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• severity of neural tube defects ranged from open anterior or posterior neuropore, small open region in the mid- or hindbrain, to complete failure of the head folds to close
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• small chorioallantoic plates with fewer labyrinthine cavities
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• formation of an extensive endothelial cell-lined vascular network was not observed
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growth/size/body
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• decreased head length
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• growth retardation: decreased crown rump and head length by E9.5, decreased somite number by E10.5
• 20% showed delayed rotation at E9.5
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nervous system
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• severity of neural tube defects ranged from open anterior or posterior neuropore, small open region in the mid- or hindbrain, to complete failure of the head folds to close
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• associated with visceral arch anomalies
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craniofacial
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• decreased head length
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cardiovascular system
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• formation of an extensive endothelial cell-lined vascular network was not observed
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• 40% showed placental hemorrhaging at E9.5
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