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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Elltm1Hhi
targeted mutation 1, Hisamaru Hirai
MGI:1933265
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Elltm1Hhi/Elltm1Hhi involves: 129X1/SvJ * C57BL/6 MGI:3618623


Genotype
MGI:3618623
hm1
Allelic
Composition		 Elltm1Hhi/Elltm1Hhi
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elltm1Hhi mutation (0 available); any Ell mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:66498 )
• homozygotes die before E6.5 but after implantation, as evident by the presence of maternal decidual tissues
• at E6.5, ~25% of offspring generated by heterozygous matings (i.e. presumed homozygotes) are already degenerative, exhibiting necrosis and hemorrhage, and undergo gradual resorption by E8.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory