All Phenotypes Clns1a<tm1Kwn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Clns1a^tm1Kwn
targeted mutation 1, Kevin D Wickman
MGI:1934011

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Clns1a^tm1Kwn/Clns1a^tm1Kwn	involves: 129 * C57BL/6J	MGI:2174690

Allelic Composition	Clns1a^tm1Kwn/Clns1a^tm1Kwn
Genetic Background	involves: 129 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clns1a^tm1Kwn mutation (1 available); any Clns1a mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mutant embryos die between E3.5 and E7.5

cellular

abnormal cell death ( J:61831 )

• homozygous ES cells could not be isolated, suggesting that this gene is essential for cellular viability

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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