Phenotypes associated with this allele

• Allele Symbol: Prnp^tm1Edin
• Allele Name: targeted mutation 1, Edinburgh University
• Allele ID: MGI:1934274
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prnp^tm1Edin/Prnp^tm1Edin	129P2/OlaHsd-Prnp^tm1Edin/EdinH	MGI:2174710

Genotype
MGI:2174710

hm1

• Allelic Composition: Prnp^tm1Edin/Prnp^tm1Edin
• Genetic Background: 129P2/OlaHsd-Prnp^tm1Edin/EdinH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal susceptibility to prion infection ( J:58820 )

• altered incubation time following infection with transmissible spongiform encephalopathy

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Creutzfeldt-Jakob disease	DOID:11949	OMIM:123400	J:58820
NOT	fatal familial insomnia	DOID:0050433	OMIM:600072	J:58820
NOT	Gerstmann-Straussler-Scheinker syndrome	DOID:4249	OMIM:137440	J:58820