Allele Symbol Allele Name Allele ID |
Phox2bDilp1 dilated pupils 1 MGI:1934628 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• abnormal Mendelian ratios suggested that some heterozygous mice die before weaning
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• exhibit no pupillary response to light
• pupils fail to constrict in response to the parasympathetic agonist, carbachol
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• exhibit no pupillary response to light
• pupils fail to constrict in response to the parasympathetic agonist, carbachol
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• exhibit severe atrophy of the ciliary ganglia at E13.5
• however, the superior cervical ganglion is normal
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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