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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbn2fp
fused phalanges
MGI:1935123
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbn2fp/Fbn2fp C3Fe(B6)-Fbn2fp/J MGI:2451231
ht2
 		Fbn2fp/Fbn2mz involves: BALB/cAnNCrl * C3H/HeH * C3HeB/FeHu * C57BL/6J MGI:4438066


Genotype
MGI:2451231
hm1
Allelic
Composition		 Fbn2fp/Fbn2fp
Genetic
Background		 C3Fe(B6)-Fbn2fp/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn2fp mutation (1 available); any Fbn2 mutation (143 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Limb clasping, reduced grip strength, and syndactyly in Fbn2mz/Fbn2mz, Fbn2fp/Fbn2fp and Fbn2mz/Fbn2fp mice

behavior/neurological

muscle

limbs/digits/tail
syndactyly ( J:13514 , J:157998 )
• variable penetrance, usually of digits 2 and 3 or 3 and 4, more rarely 2, 3 and 4; more frequent incidence in hindpaws than forepaws (J:13514)

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT distal arthrogryposis DOID:0050646 OMIM:PS108120
 J:68881




Genotype
MGI:4438066
ht2
Allelic
Composition		 Fbn2fp/Fbn2mz
Genetic
Background		 involves: BALB/cAnNCrl * C3H/HeH * C3HeB/FeHu * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn2fp mutation (1 available); any Fbn2 mutation (143 available)
Fbn2mz mutation (0 available); any Fbn2 mutation (143 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Limb clasping, reduced grip strength, and syndactyly in Fbn2mz/Fbn2mz, Fbn2fp/Fbn2fp and Fbn2mz/Fbn2fp mice

behavior/neurological

muscle




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory