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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rettm2Cos
targeted mutation 2, Frank Costantini
MGI:2136895
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rettm2Cos/Rettm2Cos involves: 129S1/Sv MGI:3583329


Genotype
MGI:3583329
hm1
Allelic
Composition		 Rettm2Cos/Rettm2Cos
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rettm2Cos mutation (0 available); any Ret mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:60659 )
• die within the first 24 hours of birth

digestive/alimentary system
abnormal intestinal peristalsis ( J:60659 )
• failure of intestinal peristalsis presumably due to aganglionosis

renal/urinary system

muscle
abnormal intestinal peristalsis ( J:60659 )
• failure of intestinal peristalsis presumably due to aganglionosis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory