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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ephx1tm1Gonz
targeted mutation 1, Frank J Gonzalez
MGI:2137236
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ephx1tm1Gonz/Ephx1tm1Gonz involves: 129X1/SvJ * C57BL/6 MGI:2175860


Genotype
MGI:2175860
hm1
Allelic
Composition		 Ephx1tm1Gonz/Ephx1tm1Gonz
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ephx1tm1Gonz mutation (2 available); any Ephx1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:56886 )
• DMBA-induced skin papillomas absent in homozygous mutant mice whereas 80% of control mice developed at least one tumor

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:56886 )
• DMBA-induced skin papillomas absent in homozygous mutant mice whereas 80% of control mice developed at least one tumor




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory