Phenotypes associated with this allele

• Allele Symbol: Sparc^tm1Cam
• Allele Name: targeted mutation 1, University of Cambridge
• Allele ID: MGI:2137432
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sparc^tm1Cam/Sparc^tm1Cam	involves: 129S/SvEv * MF1	MGI:2176498

Genotype
MGI:2176498

hm1

• Allelic Composition: Sparc^tm1Cam/Sparc^tm1Cam
• Genetic Background: involves: 129S/SvEv * MF1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

subcapsular cataract ( J:47014 )

• subcapsular cataracts begin to appear around 6 months of age

• extensive lens fiber vacuolation

• disruption of lens organization

• subsequent posterior rupture of the lens

abnormal retina layer morphology ( J:47014 )

• secondary severe disruption of the retinal layer in mice with severe cataract development