Phenotypes associated with this allele

• Allele Symbol: Crybb2^Aey2
• Allele Name: cortical and anterior suture opacity
• Allele ID: MGI:2137511
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Crybb2^Aey2/Crybb2^+	C3HeB/FeJ-Crybb2^Aey2	MGI:2175803

Genotype
MGI:2175803

ht1

• Allelic Composition: Crybb2^Aey2/Crybb2⁺
• Genetic Background: C3HeB/FeJ-Crybb2^Aey2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:70508 )

• dark particles present in the anterior suture

• dark bodies and dustlike particles noted in the subcortical zone

abnormal lens fiber morphology ( J:70508 )

• swollen and liquefied fibers noted in the anterior suture

cataract ( J:70508 )

• displayed as early as eye opening (day 12) as a diffuse opacity in the cortex and abnormally branched anterior suture

total cataract ( J:70508 )

• total opacity develops after 8 to 11 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 3 multiple types		DOID:0110269	OMIM:601547	J:70508