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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mapttm1Noh
targeted mutation 1, Nobutaka Hirokawa
MGI:2138030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mapttm1Noh/Mapttm1Noh involves: 129S4/SvJae MGI:2174969


Genotype
MGI:2174969
hm1
Allelic
Composition		 Mapttm1Noh/Mapttm1Noh
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm1Noh mutation (0 available); any Mapt mutation (430 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon morphology ( J:19030 )
• abnormal cerebellar parallel fiber axons; reduction in microtubule (MT) number and density and reduction in frequency of cross-bridges between MTs
• mice exhibit no other obvious abnormalities

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT Alzheimer's disease DOID:10652 J:19030




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory