Phenotypes associated with this allele

• Allele Symbol: Dnajb6^{Gt(ROSABetageo)6AD1Jcc}
• Allele Name: gene trap 6AD1, James C Cross
• Allele ID: MGI:2151092
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnajb6^Gt(ROSABetageo)6AD1Jcc/Dnajb6^Gt(ROSABetageo)6AD1Jcc	involves: 129S1/Sv * 129X1/SvJ * CD-1	MGI:2173120

Genotype
MGI:2173120

hm1

• Allelic Composition: Dnajb6^{Gt(ROSABetageo)6AD1Jcc}/Dnajb6^{Gt(ROSABetageo)6AD1Jcc}
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:52602 )

• no homozygotes at birth

• live embryos found only up to E11.5

• all embryos are undergoing resorption at E12.5

embryo

embryonic growth arrest ( J:52602 )

• arrested at 18 somite stage but were developing normally at 6-7 somite stage (E8.5)

• embryo turning at E9.5 is normal

decreased embryo size ( J:52602 )

• embryos are smaller than controls from E9.5 on

abnormal extraembryonic tissue morphology ( J:52602 )

absent placental labyrinth ( J:52602 )

• no placental labyrinth forms even in rare cases where a loose attachment of the allantois with chorion is seen

failure of chorioallantoic fusion ( J:52602 )

• fusion usually fails to occur

• a loose attachment of the allantois with chorion is sometimes seen

growth/size/body

decreased embryo size ( J:52602 )

• embryos are smaller than controls from E9.5 on