Phenotypes associated with this allele

• Allele Symbol: Lepr^db-dmpg
• Allele Name: dumpling
• Allele ID: MGI:2151179
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^db-dmpg/Lepr^db-dmpg	involves: B10.D2-H8^b/Sn * C57BL/6	MGI:3050671

Genotype
MGI:3050671

hm1

• Allelic Composition: Lepr^db-dmpg/Lepr^db-dmpg
• Genetic Background: involves: B10.D2-H8^b/Sn * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal pancreatic beta cell morphology ( J:83762 )

• mice have enlarged pancreatic islets with heavily degranulated beta cells but with hyperplasia and hypertrophy

growth/size/body

obese ( J:83762 )

• both males and females become morbidly obese by 12 weeks of age

homeostasis/metabolism

hyperglycemia ( J:83762 )

increased circulating insulin level ( J:83762 )