Phenotypes associated with this allele

• Allele Symbol: Lepr^db-rlpy
• Allele Name: rolypoly
• Allele ID: MGI:2151180
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^db-rlpy/Lepr^db-rlpy	involves: NU/J	MGI:3050670

Genotype
MGI:3050670

hm1

• Allelic Composition: Lepr^db-rlpy/Lepr^db-rlpy
• Genetic Background: involves: NU/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal pancreatic beta cell morphology ( J:83762 )

• mice have enlarged pancreatic islets with heavily degranulated beta cells also showing other atropic changes including fibrosis

growth/size/body

obese ( J:83762 )

• both males and females become morbidly obese by 12 weeks of age

homeostasis/metabolism

hyperglycemia ( J:83762 )

increased circulating insulin level ( J:83762 )