All Phenotypes Hoxc13<tm3.1Mrc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hoxc13^tm3.1Mrc
targeted mutation 3.1, Mario R Capecchi
MGI:2151697

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hoxc13^tm3.1Mrc/Hoxc13^tm3.1Mrc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3832429
ht2	Hoxc13^tm3.1Mrc/Hoxc13⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3832430

Allelic Composition	Hoxc13^tm3.1Mrc/Hoxc13^tm3.1Mrc
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxc13^tm3.1Mrc mutation (0 available); any Hoxc13 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

abnormal filiform papillae morphology ( J:50569 )

• phenotype is similar to that described for Hoxc13^tm1Mrc homozygous mice

craniofacial

abnormal filiform papillae morphology ( J:50569 )

• phenotype is similar to that described for Hoxc13^tm1Mrc homozygous mice

integument

abnormal hair growth ( J:50569 )

• phenotype is similar to that described for Hoxc13^tm1Mrc homozygous mice

deformed nails ( J:50569 )

• phenotype is similar to that described for Hoxc13^tm1Mrc homozygous mice

growth/size/body

abnormal filiform papillae morphology ( J:50569 )

• phenotype is similar to that described for Hoxc13^tm1Mrc homozygous mice

Allelic Composition	Hoxc13^tm3.1Mrc/Hoxc13⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxc13^tm3.1Mrc mutation (0 available); any Hoxc13 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

focal hair loss ( J:50569 )

• at some stages of the hair cycle, lower portions of the face, especially below and behind the eyes, show patchy fur

sparse hair ( J:50569 )

• the ventral coat is sparse, especially in females

• dorsal coat appears relatively normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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