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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkcetm1Msg
targeted mutation 1, Robert Messing
MGI:2152043
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Prkcetm1Msg/Prkcetm1Msg
Tg(Prnp-tTA)F959Sbp/0
Tg(tetO-Prkce)T9Msg/0 		involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J * FVB/N MGI:2651603


Genotype
MGI:2651603
cx1
Allelic
Composition		 Prkcetm1Msg/Prkcetm1Msg
Tg(Prnp-tTA)F959Sbp/0
Tg(tetO-Prkce)T9Msg/0
Genetic
Background		 involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcetm1Msg mutation (1 available); any Prkce mutation (40 available)
Tg(Prnp-tTA)F959Sbp mutation (1 available)
Tg(tetO-Prkce)T9Msg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased alcohol consumption ( J:80186 )
• in mice administered doxycycline for 2 weeks, restoration of wild-type drinking behavior
impaired righting response ( J:80186 )
• increased duration of regaining ethanol-induced loss or righting response, increase in duration of pentobarbital-induced loss or righting response




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory