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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hoxa13tm1Mrc
targeted mutation 1, Mario R Capecchi
MGI:2152348
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hoxa13tm1Mrc/Hoxa13tm1Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3846355
ht2
 		Hoxa13tm1Mrc/Hoxa13+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3846358


Genotype
MGI:3846355
hm1
Allelic
Composition		 Hoxa13tm1Mrc/Hoxa13tm1Mrc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa13tm1Mrc mutation (0 available); any Hoxa13 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:72301 )
• authors state that mice show similar phenotypes as observed in Hoxa13tm1.1Mrc homozygotes

limbs/digits/tail
abnormal limb morphology ( J:72301 )
• authors state that mice show similar phenotypes as observed in Hoxa13tm1.1Mrc homozygotes

embryo
abnormal umbilical artery morphology ( J:72301 )
• authors state that mice show similar phenotypes as observed in Hoxa13tm1.1Mrc homozygotes

cardiovascular system
abnormal umbilical artery morphology ( J:72301 )
• authors state that mice show similar phenotypes as observed in Hoxa13tm1.1Mrc homozygotes




Genotype
MGI:3846358
ht2
Allelic
Composition		 Hoxa13tm1Mrc/Hoxa13+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa13tm1Mrc mutation (0 available); any Hoxa13 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal limb morphology ( J:72301 )
• authors state that mice show similar phenotypes as observed in Hoxa13tm1.1Mrc homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory