Analysis Tools
homeostasis/metabolism
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• cold exposed-mice fail to maintain their body temperature unlike wild-type mice
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• in male mice
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• in male mice
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• in male mice
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• in mice fed a high fat diet but not standard chow
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• at 3 months, especially during the dark cycle
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• at 3 months, especially during the dark cycle
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• at 16 weeks in male, but not female, mice
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• trend at 25 weeks in male, but not female, mice
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adipose tissue
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• mouse embryonic fibroblasts exhibit a large decrease in adipogenesis compared with wild-type cells
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• at P5, interscapular brown adipose tissue exhibits decreased Oil red O staining compared to in wild-type mice
• however, brown adipose tissue mass is normal
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• 2-fold as early as 16 weeks
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• in male and female mice as early as 16 weeks
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growth/size/body
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• as early as 16 weeks
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• between 3 and 4 months
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immune system
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• white adipose tissue macrophage exhibit an activated M1 inflammatory phenotype unlike in wild-type mice
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liver/biliary system
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• in male mice at 10 weeks
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hematopoietic system
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• white adipose tissue macrophage exhibit an activated M1 inflammatory phenotype unlike in wild-type mice
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