Phenotypes associated with this allele

• Allele Symbol: Ity3^MOLF/EiJ
• Allele Name: MOLF/EiJ
• Allele ID: MGI:2154171
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ity3^MOLF/EiJ/Ity3^MOLF/EiJ	B6.MOLF-Slc11a1^r Ity3^MOLF/EiJ	MGI:3654078
hm2	Ity3^MOLF/EiJ/Ity3^MOLF/EiJ	involves: C57BL/6J * MOLF/Ei	MGI:2674304
ht3	Ity3^C57BL/6J/Ity3^MOLF/EiJ	involves: C57BL/6J * MOLF/Ei	MGI:3041977

Genotype
MGI:3654078

hm1

• Allelic Composition: Ity3^MOLF/EiJ/Ity3^MOLF/EiJ
• Genetic Background: B6.MOLF-Slc11a1^r Ity3^MOLF/EiJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal cytokine secretion ( J:108692 )

• increased serum IL-6 and CXCL-1 following flagellin administration

Genotype
MGI:2674304

hm2

• Allelic Composition: Ity3^MOLF/EiJ/Ity3^MOLF/EiJ
• Genetic Background: involves: C57BL/6J * MOLF/Ei

immune system

increased susceptibility to bacterial infection ( J:45962 , J:126552 )

• susceptibility to infection by Salmonella typhimurium (J:45962)

• decreased survival time after infection with Salmonella typhimurium (J:126552)

Genotype
MGI:3041977

ht3

• Allelic Composition: Ity3^C57BL/6J/Ity3^MOLF/EiJ
• Genetic Background: involves: C57BL/6J * MOLF/Ei

immune system

decreased susceptibility to bacterial infection ( J:45962 )

• resistance to infection by Salmonella typhimurium