Phenotypes associated with this allele

• Allele Symbol: Lmb1^C57BL/6Scr
• Allele Name: C57BL/6Scr
• Allele ID: MGI:2155873
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr	involves: C57BL/6-Fas^lpr * MRL-Fas^lpr	MGI:2674310
hm2	Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr	MRL.Cg-Lmb1^C57BL/6Scr Fas^lpr	MGI:3762859
ht3	Lmb1^C57BL/6Scr/Lmb1^MRL/MpScr	involves: C57BL/6-Fas^lpr * MRL-Fas^lpr	MGI:2674309

Genotype
MGI:2674310

hm1

• Allelic Composition: Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr
• Genetic Background: involves: C57BL/6-Fas^lpr * MRL-Fas^lpr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

enlarged spleen ( J:45708 )

immune system

enlarged spleen ( J:45708 )

enlarged lymph nodes ( J:45708 )

increased anti-double stranded DNA antibody level ( J:45708 )

• anti-dsDNA antibody production

growth/size/body

enlarged spleen ( J:45708 )

Genotype
MGI:3762859

hm2

• Allelic Composition: Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr
• Genetic Background: MRL.Cg-Lmb1^C57BL/6Scr Fas^lpr

hematopoietic system

increased spleen weight ( J:125557 )

increased double-negative T cell number ( J:125557 )

increased CD8-positive, alpha-beta T cell number ( J:125557 )

immune system

increased spleen weight ( J:125557 )

increased double-negative T cell number ( J:125557 )

increased CD8-positive, alpha-beta T cell number ( J:125557 )

growth/size/body

increased spleen weight ( J:125557 )

Genotype
MGI:2674309

ht3

• Allelic Composition: Lmb1^C57BL/6Scr/Lmb1^MRL/MpScr
• Genetic Background: involves: C57BL/6-Fas^lpr * MRL-Fas^lpr

hematopoietic system

enlarged spleen ( J:45708 )

immune system

enlarged spleen ( J:45708 )

enlarged lymph nodes ( J:45708 )

increased anti-double stranded DNA antibody level ( J:45708 )

• anti-dsDNA antibody production

growth/size/body

enlarged spleen ( J:45708 )