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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Abcb1btm2Bor
targeted mutation 2, Piet Borst
MGI:2155889
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Abcb1btm2Bor/Abcb1btm2Bor involves: 129P2/OlaHsd * FVB MGI:2386645


Genotype
MGI:2386645
hm1
Allelic
Composition		 Abcb1btm2Bor/Abcb1btm2Bor
Genetic
Background		 involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcb1btm2Bor mutation (0 available); any Abcb1b mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal xenobiotic pharmacokinetics ( J:39804 )
• altered pharmacokinetics of digoxin, with reduced elimination (and thus accumulation) of digoxin in adrenal glands and ovaries but not any other tissue
• rate of rhodamine efflux from hematopoietic progenitor cells is diminished




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory