All Phenotypes Tbc1d1<Nobq1-NZO/HlBom> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tbc1d1^{Nobq1-NZO/HlBom}
NZO/HlBom
MGI:2156037

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Nidds^SJL/NBom/? Tbc1d1^{Nobq1-NZO/HlBom}/?	involves: NZO/HlBom * SJL/NBom	MGI:2675464
ot2	Tbc1d1^{Nobq1-NZO/HlBom}/?	involves: NZO/HlBom * SJL/NBom	MGI:2175509

Allelic Composition	Nidds^SJL/NBom/? Tbc1d1^{Nobq1-NZO/HlBom}/?
Genetic Background	involves: NZO/HlBom * SJL/NBom

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nidds^SJL/NBom mutation (0 available); any Nidds mutation (0 available)
Tbc1d1^{Nobq1-NZO/HlBom} mutation (0 available); any Tbc1d1 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal glucose homeostasis ( J:78920 )

• accelerated diabetes onset on a high fat diet

Allelic Composition	Tbc1d1^{Nobq1-NZO/HlBom}/?
Genetic Background	involves: NZO/HlBom * SJL/NBom

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbc1d1^{Nobq1-NZO/HlBom} mutation (0 available); any Tbc1d1 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

increased white adipose tissue amount ( J:66744 )

homeostasis/metabolism

increased circulating insulin level ( J:66744 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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