adipose tissue
• reduced volume of epidymal fat
|
endocrine/exocrine glands
• cavities in the adrenal medulla
• decrease in amount of capillaries
• normal adrenal cortex
• normal levels of catecholamine metabolites in urine, indicating normal adrenal function
|
growth/size/body
• 30% reduction at 9 months of age
|
uterus cyst
(
J:62260
)
• cystic formations
|
homeostasis/metabolism
N |
• normal serum cholesterol, glucose and cholesterol levels
• normal serum creatine levels
• normal blood urea nitrogen levels
|
renal/urinary system
• severely reduced corticomedullary tissue
|
• poorly developed or absent papillae
|
• poorly developed or absent papillae
|
• greatly enlargeed caliceal space, first evident at 1 wk and progressing afterward
|
• accumulation of collagen between epithelial and smooth muscle cell layers
|
• retraction of the ureteropelvic junction inside the hilium, which was surrounded by fibrous tissue
|
• obstruction of the ureteropelvic junction
|
reproductive system
uterus cyst
(
J:62260
)
• cystic formations
|
• reduced number of implantations observed 10 dpc
|
• 13% of females became pregnant after plug formation; males were fertile
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
urinary tract obstruction | DOID:5200 | J:62260 |