Phenotypes associated with this allele

• Allele Symbol: Mbtps1^{Gt(PST115)Byg}
• Allele Name: gene trap PST115, BayGenomics
• Allele ID: MGI:2156182
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mbtps1^Gt(PST115)Byg/Mbtps1^Gt(PST115)Byg	involves: 129P2/OlaHsd * C57BL/6	MGI:3029274
ht2	Mbtps1^Gt(PST115)Byg/Mbtps1^+	involves: 129P2/OlaHsd * C57BL/6	MGI:3837829
ht3	Mbtps1^Gt(PST115)Byg/Mbtps1^wrt	involves: 129P2/OlaHsd * C57BL/6	MGI:3837828

Genotype
MGI:3029274

hm1

• Allelic Composition: Mbtps1^{Gt(PST115)Byg}/Mbtps1^{Gt(PST115)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality at implantation, complete penetrance ( J:70273 )

• all embryos die at the implantation stage

embryo

abnormal germ layer development ( J:70273 )

inner cell mass degeneration ( J:70273 )

• embryos grown in culture fail to maintain the inner cell mass

Genotype
MGI:3837829

ht2

• Allelic Composition: Mbtps1^{Gt(PST115)Byg}/Mbtps1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

mortality/aging

prenatal lethality, incomplete penetrance ( J:146454 )

• only half the expected number of pups with this genotype are born

Genotype
MGI:3837828

ht3

• Allelic Composition: Mbtps1^{Gt(PST115)Byg}/Mbtps1^wrt
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

mortality/aging

prenatal lethality, complete penetrance ( J:146454 )

• no compound heterozygote pups are born alive