normal phenotype
• Background Sensitivity: unlike animals on a congenic B6 background, these animals were viable and healthy to adulthood
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Allele Symbol Allele Name Allele ID |
Zfp110tm1Mpin targeted mutation 1, Max-Planck-Institute for Neurobiology MGI:2156881 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• Background Sensitivity: unlike animals on a congenic B6 background, these animals were viable and healthy to adulthood
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• death around E12
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• severe growth retardation evident at E12
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• severe growth retardation evident at E12
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• incomplete penetrance, 20% of progeny die before or shortly after birth
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• up to 70% reduction in testis weight, age-dependent
• males fertile and no other obvious morphological alterations in testis
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• up to 70% reduction in testis weight, age-dependent
• males fertile and no other obvious morphological alterations in testis
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• reduced levels of cell death in developing retina compared to littermate controls
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• reduced levels of cell death in developing retina compared to littermate controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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