Analysis Tools|
Allele Symbol Allele Name Allele ID |
Rasgrf1tm1Toc targeted mutation 1, Bruno Tocque MGI:2157017 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• when the mutant allele is paternally inherited
• weight at 3-4 weeks of age is reduced 25% in females and 30% in males
• adults are persistently 15-25% smaller
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• postnatal growth is slower when the mutant allele is paternally inherited
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• pituitary growth hormone levels are reduced 42-53% when the mutant allele is paternally inherited
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• reduced 32-40% at 4 weeks of age when the mutant allele is paternally inherited
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• contained 42-53% less growth hormone than the wild-type controls when the mutant allele is paternally inherited
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• pituitary growth hormone levels are reduced 42-53% when the mutant allele is paternally inherited
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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